Compounds called hericenones (hence the mushroom’s Latin name Hericium erinaceus) present in the fruiting bodies of lion’s mane were found to induce the synthesis of the nerve growth factor. This has been shown to have an ameliorative effect in Alzheimer’s treatment and cognitive function.
Polysaccharides, as well as novel phenol and fatty acid compounds present in Lion’s Mane may have chemotherapeutic effects on certain cancers such as stomach, esophageal, and skin cancers, among others.
K. Mori, S. Inatomi, K. Ouchi, Y. Azumi, and T. Tuchida. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double‐blind placebo‐controlled clinical trial. Phytotherapy. Research. 23. 367-372 (2009)
T. Mizuno, Bioactive substances in Hericium Erinaceus (Bull.: Fr.) Pers. (Yamabushitake), and its medicinal utilization. International Journal of Medicinal Mushrooms. 1 (2). 105-119 (1999)